William Stokes – His Life and Work. By his son Sir William Stokes, 1898.
This review was written on June 4th 2004
I read
the biography of Dr. William Stokes by his son, Sir William Stokes, in May
2002. It was published by T. Fisher Unwin of London in 1898 in the Masters
of Medicine series of
biographies. I had read this short
biography many years ago and had been much influenced by the life of William
Stokes and by the contribution he made to the advancement of medicine and to
the standards of the medical profession.
It was one of the books, mostly biographies, which had a profound
influence on my own career and which was important in enhancing my appreciation
of my role as a doctor.
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William Stokes |
Stokes
was born in Dublin in 1804 and died in 1878. He was descended from a
distinguished family which had
lived in Ireland for five generations and which first arrived from
Gloucestershire in 1680 when his predecessor, Gabriel Stokes, an engineer, took
up the position of Deputy Surveyor in Ireland. After qualifying in Edinburgh, Stokes returned to Dublin
where he was soon appointed to the Meath Hospital. It was here that he
established his reputation as a teacher and physician.
Sir
William Stokes, his son and biographer, qualified as a doctor in Dublin and,
unlike his father, trained as a surgeon and was also attached to the Meath
Hospital as well as the Royal College of Surgeons.
William Stokes
worked closely with a senior colleague in the Meath, Robert Graves. Both these
physicians played an outstanding part in enhancing the reputation of the Irish
School of Medicine. Indeed, while
they were the leading pair to advance the mid-nineteenth century reputation of
the Irish school, they were only two of a very distinguished group of
progressive physicians and surgeons who brought great honour and fame to Dublin
medicine.
Long
before I had read Stokes’ biography, I was aware of his reputation,
particularly in the field of cardiology.
He had published two important monographs, the first, which brought him
early international notice, was Diseases of the Chest published in 1837. My interest, however, was mainly in his
second major publication, Diseases of the Heart and Aorta, which was published in 1850. This brought him added fame and, like
his previous book, it was translated into the principle European languages.
I had
read Diseases of the Heart and Aorta in the early 1950s after my return to Ireland following my
postgraduate training in clinical cardiology, and I delivered an address to the
Royal Irish Academy of Medicine in 1955, entitled Diseases of the Heart and
Aorta – a Modern Clinical Review. This address was published in the Irish Journal of Medical
Science that year. It
was subsequently reproduced many years later as an addendum when a facsimile
copy of Stokes’s work was published by the Classics of Cardiology Library in
the United States in 1985.
At this
time I had become interested in the Irish contributions to cardiology during the
nineteenth century. I later published a paper O’Bryan Bellingham - a
Centenary Tribute.
Bellingham was a physician appointed to St. Vincent’s Hospital about 1840 and
had written this book mainly about aneurysm but it included much about the
heart. I published a few papers about the articles on heart disease which made
Sir Dominic Corrigan famous. Finally, before my commitment to research and the
management of coronary disease in early 1960 occupied an increasing amount of
my time, I published The Views of the 19th Century Irish Cardiologists on
Coronary Artery Disease, a paper I had read in Boston at the invitation of Dr. Paul White.
So ended
my brief interest in
probing medical history. I had been warned by my senior colleague and mentor, Dr.
Patsy O’Farrell, that writing medical history was one of the most compelling addictions
known to Man, but my escape from such a fate was inevitable as the coronary
epidemic gathered pace at the end of the 1950s and as I found myself responsible for
all coronary and other heart problems admitted to St. Vincent’s Hospital.
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The Meath hospital in 1822 |
Stokes
and Graves were responsible for the dramatic change from the obscurantism and
the empiricism of medicine which existed in the early part of the 1800s to the
hands-on clinical approach to disease. This new clinical approach was the
bedrock of good medical practice and was based on careful history taking and
physical examination. Such practice depended on a detailed knowledge of
anatomy, pathology and physiology, correlated with the patient’s symptoms and
physical signs. They also led a change in medical practice from the irrational
cupping, bleeding, purging and starvation of their predecessors to less harmful
interventions.
Stokes
made an outstanding contribution to medicine when he inaugurated the
Pathological Society in Dublin in 1838. The meetings were held weekly and were
a forerunner of our current grand rounds and death conferences. It was an
immediate and popular innovation and was widely attended by medical people at
the time, including teaching hospital staff, outside practitioners and
students. Numerous pathological
specimens were presented with the clinical details of each case and such were
the many contributions to the society that discussion was not permitted because
of time restrictions.
It was
largely through his intervention that Trinity College set up the first
Department of Hygiene or Preventive Medicine and Public Health in these
Islands, and that the University was the first in these islands to provide a
diploma in this subject. Perhaps
one factor which quickened my own involvement in preventive medicine was
Stokes’s vision in this particular area. He had a passionate interest in what
we now call health promotion and clearly considered it as an integral part of
the doctor’s function. Later, as President of the British Medical Association,
on the occasion of its annual general meeting in Ireland in 1867, he addressed
the audience and was optimistic about the participation of physicians in
prevention, but sadly, as I can confirm, the subject received little interest
from the organised profession at least until a few years ago. The importance of
including prevention and health promotion as in integral part of medical
practice was raised by me at a few meetings of the Irish Medical Association at
the time of my Presidency. It was received by all my colleagues with the
classical glazed look of the indifferent.
Stokes
had an intense interest in the reputation and the welfare of the medical
profession but he was also passionately interested in his patients and in the
standards and ethos of his hospital.
He was nationalist in the sense that he had a singular patriotism for
his country and an intense interest in its culture, its history and its
welfare. He combined his
patriotism with a firm belief that the welfare of the country was best assured
by its continued representation in Westminster. He was totally opposed to the
Repeal movements which were so active in Ireland during the years following the
Union. Yet he had a great sympathy and a great affection for many of our great
repealers and separatists of the time, such as Wolfe Tone, Robert Emmet, Thomas
Davis and, later, Isaac Butt.
Stokes
had a profound sympathy for the poor and particularly for their sufferings
during the many famines that occurred during the earlier part of the nineteenth
century. He believed that the reputation and the welfare of the profession
would be assured by our doing everything possible to improve the lot of society
and to provide a compassionate service for our patients. I was a member of the General and
Executive Councils of the Irish Medical Association for about twelve years.
Before and during that time the Association had a clear commitment to the
public welfare and a better health service. In 1974 we published a working
party report advocating a compulsory insurance service for the entire
population of the country but this proposal, while warmly supported by the
members of the Association and still widely advocated, has not yet been
established thirty years later. There was a sense of responsibility about the
role of the profession in society among doctors at the time. It certainly
enhanced the reputation of the profession with the public and appeared to do no
harm to our own financial circumstances. While things may have changed now as
we live in more materialistic and secular times, it was evident that the
Association’s more altruistic motives were an expression of the traditions
established one hundred years earlier by Stokes and his colleagues.
Stokes
travelled much during his lifetime, both on the continent and throughout the
island of Ireland. He was closely
associated with Lord Dunraven, George Petrie and the many other historians,
archaeologists, architects and amateurs, including some doctors, who were doing
so much at this time of enlightenment to create an interest in Irish history,
culture and the artifacts of the past.
Stokes became an intimate friend of George Petrie who contributed so
much to the recording of Irish antiquities and ecclesiastical architecture,
both pre-Christian and post-Christian, and whose seminal work, Round Towers
of Ireland is in my
father’s library. Petrie was only one of many, mainly Protestant, professional
and middle class, who provided the thrust of the rapidly expanding movement of
enquiry into the history, antiquities, culture and language of the old Irish
and Celtic tradition. Many of these pioneers, like Stokes and William Wilde,
were doctors. The interest of these new patriots was to lead to the Celtic
Twilight, advanced by Yeats, Standish O’Grady, Padric Colum, James Stephens and
many others, whose books have an honoured place in my father’s library. And
there were a myriad of others who, free from the narrow prejudices of religion
and politics, contributed in different ways to the great revival of interest in
Ireland’s past, and who could all claim the distinction of being true patriots.
Musing
about his interest in the Irish countryside and its archaeology and
antiquities, William Stokes prophesied (page 60 of his biography)
........in truth, a little time will level these ancient
castles and their high borne and their honourable inhabitants and the feelings
which their communion creates, and
then “utility” will have it’s
reign, and “common sense”, laughing at the past and the beautiful, will build factories with the remains of
history, make money, and die.
My
latter days as a cardiologist were almost entirely devoted to the treatment of
coronary disease, and to research into its natural history, causes and
prevention. I also had bedside teaching responsibilities. The coronary epidemic
peaked in the early sixties and affected all adults and both sexes at this
time. It was to prove the greatest epidemic of the latter half of the twentieth
century in the Western world.
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The ECG; the early years. |
There
was much confusion in the mid-nineteenth century about the exact nature of
coronary disease. Indeed the confusion about the pathological basis and the
clinical manifestations of coronary
disease still existed up to the time I qualified in 1945. It was only with the rapid advances in
clinical cardiology immediately after the last Great War and the widespread
application of electrocardiography then, that the precise pathological nature
and diagnosis of myocardial infarction and chronic angina of effort was
appreciated by contemporary cardiologists. We were to wait a few more years
before other acute coronary syndromes, such as unstable angina and non-Q wave
infarction, were recognised, and it required many more years still, and the
arrival of the coronary care unit in the mid and late 1960s, before the precise
diagnosis of coronary heart disease extended to the entire profession.
Stokes
was familiar with the diagnosis of angina but had no insight into its
pathological basis, the narrowing of the coronary arteries by atherosclerosis,
nor did the symptoms of the disease have the same diagnostic specificity it has
to-day. He was not familiar with the pathological concept of myocardial
infarction nor was there any great significance attached to disease of the
coronary arteries. He used the term ‘fatty heart’, probably referring to
examples of infarction. Another term in use at the time by pathologists was
haemorrhagic myocarditis, almost certainly referring to acute heart attacks.
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Practice what ye preach... |
There
was no rational treatment available for the treatment of heart disease in
Stokes’s time nor indeed had physicians much to offer in terms of treatment for
any serious medical condition until after the last Great War. However, he did
recommend exercise in the treatment of heart cases, thus preceding by nearly one
hundred and fifty years the acceptance by the profession of the use of
graduated aerobic exercise in the prevention and management of coronary heart
disease. His exercise prescription
is mentioned in his book “Diseases of the Heart and Aorta” and is quoted on
page 139 of his son’s biography.
He advocates walks in the highlands of Ireland, Scotland and Switzerland
for his heart patients.
Reading
Stokes’s life made a profound impression on me and greatly enhanced my pride in
the medical profession and my interest in clinical medicine. It must also have
enhanced my commitment to the wider aspects of prevention. However, I had read the life of William
Osler (by his colleague in Johns Hopkins, the neurosurgeon Harvey Cushing)
about the time I qualified and this too had a great influence on my
appreciation of the role of doctors in society and of the huge satisfaction to
be derived by those who were lucky enough to have or to acquire a vocation
which conferred a commitment to the welfare of patients, society and to the
ancient ethos of the profession. This commitment can only be acquired by
sharing a visceral insight into the patient’s plight as if it were one’s own
personal problem.
Osler
was perhaps the greatest physician of his time and certainly earned the greatest reputation internationally.
Born and bred in Canada where he qualified as a doctor in McGill
University, he moved and established his reputation in Philadelphia and subsequently
in the John’s Hopkins Hospital in Baltimore. His essays, principally aimed at medical students and his
own colleagues, have been published frequently and are a clear expression of
his great humanity, his culture and his appreciation of how the medical
profession can contribute so much to the welfare of society. His best known essay, Aequanimitas, certainly had a profound effect on my
own life and attitudes, and encouraged a maturity to face the slings and arrows
of outrageous fortune in a philosophical way. Like Stokes, he was totally committed to clinical medicine
as manifested by careful history taking and by thorough physical
examination.
I like
to think that, when I was trained in London in internal medicine and
cardiology, I developed the same appreciation of the importance of clinical
medicine. I slowly acquired an insight into clinical practice by the mental
co-ordination of anatomy, physiology, pathology as the basis of symptoms and
physical signs leading to an integrated appreciation of disease. Like Osler and Stokes and many other
predecessors, I was fortunate that I had little access to special
investigations and I had no personal or financial interest in any matters
outside my consultation work and my clinical practice.
Another
source of inspiration to me was Paul White’s “Heart Disease” which was first
published in 1935. I read the 1944 second edition when I was a final year
medical student. Paul White was
popularly known as General Eisenhower’s physician but this title endowed on him
by the media overshadowed his great clinical reputation as one of the early and
most progressive cardiologists in the United States. His book is remarkable in that he lays as much importance on
the prevention of heart disease, both primary and secondary, as he does on the
limited treatment which was available at that time. He had many of the qualities of Stokes and Osler and his
book had an immediate effect on me in that I was determined to specialise in
cardiology after qualification. I was to resist offers by my own teaching
hospital to specialise in anaesthesia or to take up a surgical career. Instead,
I spent four months unemployed after I qualified and completed my one-year
residence at St Vincent’s Hospital. I eventually found a locum job in London
where I later attended the National Heart Hospital as a post-graduate
student.
Paul
White was a man of wide vision with an intense interest in the role the
profession could play in encouraging the public health. He played a major role
in the American Heart Association and subsequently he was to encourage the
world-wide spread of the Heart Foundation concept. I met Paul White on several occasions during my subsequent
visits to the United States, including his invitation to me to speak to the
Massachusetts Medical Society about the nineteenth century cardiologists in
Dublin. He was always interested in his junior colleagues and students, and he
was, of course, the doyen of the medical faculty at the Massachusetts General
Hospital. It was his custom to
invite all visitors to his home where, among the other aspects of his
hospitality, one was expected to mow the lawn in front of his house. This was all part of his philosophy
that exercise was not only important from the physiological and health points
of view, but particularly from the point of view of the management of coronary
disease. He was an early pioneer
in advocating graduated exercise for coronary disease but he was preceded by
one hundred years by William Stokes who advocated graduated exercise for the
“fatty heart”.
Stokes,
Osler and White had much in common as physicians. Reading their works was
certainly a great inspiration to me and the source of the great satisfaction I
enjoyed during my years as a clinical cardiologist. I could claim with confidence that I never knew a moment of
ennui or depression while I was working in the wards of the hospital, in the
outpatients department or in my private consulting room. I was fortunate that, indifferent as I
was to the prospect of entering the medical profession and bored as I was by my
first three academic years on the university campus, I had the good fortune to
find myself in a profession which amply suited my temperament and my social
background. Stoke’s commitment to
his patients inspired him more than any other consideration. It is surely the
most important ingredient of the Hippocratic spirit.